Move up for a scene, then get ready to kill one guy attacking you, then the guy on your family. You then get a sword and help as you finish off the gang, and remember, behind enemies with your hidden blade equipped is an instant kill, other than that just use your sword counter - no counters with the blade like last game, ugh.
Casa Dolce Casa
Just follow Mario up to the villa.
Then you head down to the market below for some stuff. You must by the greaves for 1140f, and dagger for 475f. Then fill up on medicine at the nearby doctor.
Easy peasy, just above where the tour ends.
1. Roof of the building SW from the practice ring.
2. Above the entrance to the town, use the side walls to get up there.
3. On the roof of the country house to the NE of town, outside the walls.
4. On the house west, outside town.
Practice Makes Perfect
Talk with you gals, then your uncle.
You first learn the quickstep, which will be nice for using the blade for quicker kills in battle.
Then do a few counter kills and taunts, and then you pick up the escape skill, which you probably can do anyway.
Finally, just use your skills to defeat Mario, well except for escaping. Just counter, quick step, and slash him to win.
This mission ends upon re-entering Mario's room. Then stop by to visit the family to learn about the feathers, which the three you got earlier do not count towards.
Set off on a horse, stabled outside the town, in the direction of Tuscany.
What Goes Around
Mission up ahead, cut across the field to dismount and talk to Mario.
Run with him up the hill for a quick scene. Select your knives from the inventory wheel, then go up the wall and take out the first archer. Jump over a roof or two and pick off the next archer. Get on the courtyard and take out the third archer on another roof. Then open the gate using the crank nearby.
Now you must fight about 10 guards nearby. Just use your sword or clean views with your knives. Even with your sword, you can instantly kill enemies by attacking their backs. Take them out and just run north to the well and talk to the guy.
*NOTE: By attacking these guards, your notoriety has gone up, so the poster, herald, and officials icons have popped up on your map. No need to do them now, just FYI.*
Up ahead you will help Mario's men, and you only need to attack a few before Mario has you move onto the next marker. Now your meter is very high, but you can't just tear down a few posters, I believe they are not actually in the world while in a mission. Either way, just follow the roofs to the marker.
After the scene, hop down to the northeast roof, then over to the wall. Climb up this wall, hang over the side, lock onto Vieri, get up, do the free run and then press the grasp button, and if you get him onto the ground, just kill him; otherwise feel free to use your blade while you fight, and I think now you can counter kill with the blade.
You'll be back in the villa after the deed is done.
*NOTE: You can take this time to find the statuettes, which are covered in the extra stuff portion of this guide.*
A Change of Plans
Talk to Mario, follow, and then go to the codex wall in his study.
Then to the viewpoint on the roof which we got earlier, but this time it will reveal 4 nearby codex pages.
#1. Just to the southeast of the viewpoint, on the ground by some boxes.
#2. To the far southwest, in a dark alley on the ground.
#3. On the very east side of the town, in another alley.
#4. Take a horse east of town, and find this behind a little shack.